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A single amino acid exchange converts FocA into a unidirectional efflux channel for formate

During mixed-acid fermentation, Escherichia coli initially translocates formate out of the cell, but re-imports it at lower pH. This is performed by FocA, the archetype of the formate-nitrite transporter (FNT) family of pentameric anion channels. Each protomer of FocA has a hydrophobic pore through...

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Detalles Bibliográficos
Autores principales:	Kammel, Michelle, Trebbin, Oliver, Pinske, Constanze, Sawers, R. Gary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2022
Materias:	Microbial Physiology, Biochemistry and Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914244/ https://www.ncbi.nlm.nih.gov/pubmed/35084298 http://dx.doi.org/10.1099/mic.0.001132

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