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Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104)

Early studies revealed that chicken embryos incubated with a rare analog of l-proline, 4-oxo-l-proline, showed increased levels of the metabolite 4-hydroxy-l-proline. In 1962, 4-oxo-l-proline reductase, an enzyme responsible for the reduction of 4-oxo-l-proline, was partially purified from rabbit ki...

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Detalles Bibliográficos
Autores principales: Kwiatkowski, Sebastian, Bozko, Maria, Zarod, Michal, Witecka, Apolonia, Kocdemir, Kubra, Jagielski, Adam K., Drozak, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914325/
https://www.ncbi.nlm.nih.gov/pubmed/35150746
http://dx.doi.org/10.1016/j.jbc.2022.101708