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Expanding polysaccharide–protein coupling of glycoconjugate vaccines
For the preparation of glycoconjugate vaccines, polysaccharide antigens can usually be chemically modified to generate reactive functional groups (e.g., the formation of aldehyde groups by periodate oxidation of adjacent diols) for covalent coupling with proteins. In a recent issue of JBC, Duke et a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Biochemistry and Molecular Biology
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914364/ https://www.ncbi.nlm.nih.gov/pubmed/35202656 http://dx.doi.org/10.1016/j.jbc.2022.101755 |