Cargando…

Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells

Pancreatic ductal adenocarcinoma (PDAC) is characterized by poor prognosis and high mortality. Transforming growth factor-β (TGF-β) plays a key role in PDAC tumor progression, which is often associated with aberrant glycosylation. However, how PDAC cells respond to TGF-β and the role of glycosylatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jing, Zhang, Zejian, Holst, Stephanie, Blöchl, Constantin, Madunic, Katarina, Wuhrer, Manfred, ten Dijke, Peter, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914387/
https://www.ncbi.nlm.nih.gov/pubmed/35151689
http://dx.doi.org/10.1016/j.jbc.2022.101717