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Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells
Pancreatic ductal adenocarcinoma (PDAC) is characterized by poor prognosis and high mortality. Transforming growth factor-β (TGF-β) plays a key role in PDAC tumor progression, which is often associated with aberrant glycosylation. However, how PDAC cells respond to TGF-β and the role of glycosylatio...
Autores principales: | Zhang, Jing, Zhang, Zejian, Holst, Stephanie, Blöchl, Constantin, Madunic, Katarina, Wuhrer, Manfred, ten Dijke, Peter, Zhang, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914387/ https://www.ncbi.nlm.nih.gov/pubmed/35151689 http://dx.doi.org/10.1016/j.jbc.2022.101717 |
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