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Influence of alectinib and crizotinib on ionizing radiation - in vitro analysis of ALK/ROS1-wildtype lung tissue cells

(1) Background: Just little is known about the interaction of ALK/ROS1-targeting kinase inhibitors with ionizing radiation (IR), particularly regarding side effects. We investigated the toxicity in two different lung cell lines both ALK/ROS1 wildtype (healthy and tumor origin) as representatives for...

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Detalles Bibliográficos
Autores principales: Jost, Tina, Schultz, Ann-Kristin, Frey, Benjamin, Vu, Jennifer, Fietkau, Rainer, Distel, Luitpold V., Hecht, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914391/
https://www.ncbi.nlm.nih.gov/pubmed/35278911
http://dx.doi.org/10.1016/j.neo.2022.100780