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BRAF Mutations Are Associated with Poor Survival Outcomes in Advanced-stage Mismatch Repair-deficient/Microsatellite High Colorectal Cancer

BACKGROUND: Mismatch repair-deficient (MMR-D)/microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC) is a unique disease entity with growing interest given the rise of young-onset CRC. Given its heterogeneous behavior and potential for highly effective treatment outcomes, we sou...

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Detalles Bibliográficos
Autores principales: Tan, Elaine, Whiting, Junmin, Xie, Hao, Imanirad, Iman, Carballido, Estrella, Felder, Seth, Frakes, Jessica, Mo, Quanxing, Walko, Christine, Permuth, Jennifer B, Sommerer, Katelyn, Kim, Richard, Anaya, Daniel A, Fleming, Jason B, Sahin, Ibrahim Halil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914499/
https://www.ncbi.nlm.nih.gov/pubmed/35274712
http://dx.doi.org/10.1093/oncolo/oyab055