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Extracellular vesicles promotes liver metastasis of lung cancer by ALAHM increasing hepatocellular secretion of HGF

Tumor-derived extracellular vesicles (EVs) are involved in tumor metastasis. Highly enriched lncRNA-ALAHM was identified from serum EVs of lung adenocarcinoma (LUAD) patients with liver metastasis by high-throughput sequencing. A mouse model of in situ lung cancer was used to determine the effect of...

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Detalles Bibliográficos
Autores principales: Jiang, Chunyang, Li, Xu, Sun, Bingsheng, Zhang, Na, Li, Jing, Yue, Shijing, Hu, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914534/
https://www.ncbi.nlm.nih.gov/pubmed/35281743
http://dx.doi.org/10.1016/j.isci.2022.103984