Targeting CB2 and TRPV1: Computational Approaches for the Identification of Dual Modulators

Both metabotropic (CBRs) and ionotropic cannabinoid receptors (ICRs) have implications in a range of neurological disorders. The metabotropic canonical CBRs CB1 and CB2 are highly implicated in these pathological events. However, selective targeting at CB2 versus CB1 offers optimized pharmacology du...

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Detalles Bibliográficos
Autores principales: Morales, Paula, Muller, Chanté, Jagerovic, Nadine, Reggio, Patricia H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914543/
https://www.ncbi.nlm.nih.gov/pubmed/35281260
http://dx.doi.org/10.3389/fmolb.2022.841190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914543/
https://www.ncbi.nlm.nih.gov/pubmed/35281260
http://dx.doi.org/10.3389/fmolb.2022.841190

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