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Dopamine neuron stimulation induces context-dependent abnormal involuntary movements in healthy rats
With continued levodopa treatment, most patients with Parkinson disease (PD) develop levodopa-induced dyskinesias (LIDs)—abnormal involuntary movements (AIMs) characterized primarily by chorea. Clinically, LIDs depend on nigrostriatal degeneration and sensitization to repeated levodopa doses. Howeve...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914546/ https://www.ncbi.nlm.nih.gov/pubmed/35281727 http://dx.doi.org/10.1016/j.isci.2022.103974 |