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The TL1A-DR3 Axis in Asthma: Membrane-Bound and Secreted TL1A Co-Determined the Development of Airway Remodeling

PURPOSE: Tumor necrosis factor-like ligand 1A (TL1A), especially its secreted form, has been shown to contribute to eosinophilic inflammation and mucus production, cardinal features of asthma, through its receptor, death receptor 3 (DR3). However, the role of the TL1A-DR3 axis in asthma, especially...

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Detalles Bibliográficos
Autores principales: Zhang, Jintao, Zhang, Dong, Pan, Yun, Liu, Xiaofei, Xu, Jiawei, Qiao, Xinrui, Cui, Wenjing, Dong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914606/
https://www.ncbi.nlm.nih.gov/pubmed/35255540
http://dx.doi.org/10.4168/aair.2022.14.2.233