Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations

Stimulator of Interferon Genes (STING) is a cytosolic sensor of cyclic dinucleotides (CDNs). The activation of dendritic cells (DC) via the STING pathway, and their subsequent production of type I interferon (IFN) is considered central to eradicating tumours in mouse models. However, this contributi...

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Detalles Bibliográficos
Autores principales: Pang, Ee Shan, Daraj, Ghazal, Balka, Katherine R., De Nardo, Dominic, Macri, Christophe, Hochrein, Hubertus, Masterman, Kelly-Anne, Tan, Peck S., Shoppee, Angus, Magill, Zoe, Jahan, Nazneen, Bafit, Mariam, Zhan, Yifan, Kile, Benjamin T., Lawlor, Kate E., Radford, Kristen J., Wright, Mark D., O’Keeffe, Meredith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914948/
https://www.ncbi.nlm.nih.gov/pubmed/35281062
http://dx.doi.org/10.3389/fimmu.2022.794776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914948/
https://www.ncbi.nlm.nih.gov/pubmed/35281062
http://dx.doi.org/10.3389/fimmu.2022.794776

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