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Analyzing cachectic phenotypes in the muscle and fat body of Drosophila larvae

Drosophila has become a popular model for examining the metabolic wasting syndrome, cachexia, characterized by degradation of muscles and fat. Here we present a protocol for quick and consistent scoring of muscle detachment, fat body lipid droplet size, and extracellular matrix (ECM) quantifications...

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Detalles Bibliográficos
Autores principales: Dark, Callum, Cheung, Shane, Cheng, Louise Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915010/
https://www.ncbi.nlm.nih.gov/pubmed/35284841
http://dx.doi.org/10.1016/j.xpro.2022.101230