Cargando…

K(+)‐independent Kir blockade by external Cs(+) and Ba(2+)

Cations such as Cs(+) and Ba(2+) are known to block K(+) currents by entering an open channel and binding to the selectivity filter, where they obstruct the pore and block diffusion of the permeant ion. This obstruction is voltage‐ and K(+)‐dependent and is relieved by the trans permeant ion flux. T...

Descripción completa

Detalles Bibliográficos
Autor principal: Gilles, Ouanounou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915156/
https://www.ncbi.nlm.nih.gov/pubmed/35274814
http://dx.doi.org/10.14814/phy2.15200