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Advanced Glycation End-Products (AGEs) of Lysine and Effects of Anti-TCR/Anti-TNF-α Antibody-Based Therapy in the LEW.1AR1-iddm Rat, an Animal Model of Human Type 1 Diabetes

The LEW.1AR1-iddm rat is an animal model of human type 1 diabetes (T1D). Previously, we have shown that combination with anti-TCR/anti-TNF-α antibody-based therapy re-established normoglycemia and increased proteinic arginine-dimethylation in the spleen, yet not in the pancreas. High blood glucose i...

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Detalles Bibliográficos
Autores principales: Baskal, Svetlana, Tsikas, Stefanos A., Begou, Olga, Bollenbach, Alexander, Lenzen, Sigurd, Jörns, Anne, Tsikas, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915180/
https://www.ncbi.nlm.nih.gov/pubmed/35163462
http://dx.doi.org/10.3390/ijms23031541