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CD47 Blockade Accelerates Blood Clearance and Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage

AIMS: Subarachnoid hemorrhage (SAH) is a devastating stroke subtype. Following SAH, erythrocyte lysis contributes to cell death and brain injuries. Blockage of the anti-phagocytic receptor Cluster of Differentiation 47 (CD47) enhances phagocyte clearance of erythrocytes, though it has not been well-...

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Detalles Bibliográficos
Autores principales: Xu, Chao-ran, Li, Jian-ru, Jiang, Shao-wei, Wan, Liang, Zhang, Xin, Xia, Lei, Hua, Xu-ming, Li, Shi-ting, Chen, Huai-jun, Fu, Xiong-jie, Jing, Chao-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915201/
https://www.ncbi.nlm.nih.gov/pubmed/35281006
http://dx.doi.org/10.3389/fimmu.2022.823999