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Uptake of the multi-arm multi-stage (MAMS) adaptive platform approach: a trial-registry review of late-phase randomised clinical trials

BACKGROUND: For medical conditions with numerous interventions worthy of investigation, there are many advantages of a multi-arm multi-stage (MAMS) platform trial approach. However, there is currently limited knowledge on uptake of the MAMS design, especially in the late-phase setting. We sought to...

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Detalles Bibliográficos
Autores principales: Noor, Nurulamin M, Love, Sharon B, Isaacs, Talia, Kaplan, Richard, Parmar, Mahesh K B, Sydes, Matthew R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915371/
https://www.ncbi.nlm.nih.gov/pubmed/35273052
http://dx.doi.org/10.1136/bmjopen-2021-055615