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Caging Polycations: Effect of Increasing Confinement on the Modes of Interaction of Spermidine(3+) With DNA Double Helices

Polyamines have important roles in the modulation of the cellular function and are ubiquitous in cells. The polyamines putrescine(2+), spermidine(3+), and spermine(4+) represent the most abundant organic counterions of the negatively charged DNA in the cellular nucleus. These polyamines are known to...

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Detalles Bibliográficos
Autores principales: Vasiliu, Tudor, Mocci, Francesca, Laaksonen, Aatto, Engelbrecht, Leon De Villiers, Perepelytsya, Sergiy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915389/
https://www.ncbi.nlm.nih.gov/pubmed/35281557
http://dx.doi.org/10.3389/fchem.2022.836994