LKB1 alleviates high glucose- and high fat-induced inflammation and the expression of GnRH and sexual precocity-related genes, in mouse hypothalamic cells by activating the AMPK/FOXO1 signaling pathway

Precocious puberty (PP) is a developmental disorder. Hypothalamic cells can produce gonadotropin-releasing hormone (GnRH), the final output of neuroendocrine regulation that occurs during puberty. The aim of the present study was to investigate the role of live kinase B1 (LKB1), also known as serine...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Guan, Limei, Zhou, Qing, Huang, Hailong, Xu, Liangpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915400/
https://www.ncbi.nlm.nih.gov/pubmed/35234270
http://dx.doi.org/10.3892/mmr.2022.12659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915400/
https://www.ncbi.nlm.nih.gov/pubmed/35234270
http://dx.doi.org/10.3892/mmr.2022.12659

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