Roxadustat (FG-4592) Facilitates Recovery From Renal Damage by Ameliorating Mitochondrial Dysfunction Induced by Folic Acid

Incomplete recovery from acute kidney injury induced by folic acid is a major risk factor for progression to chronic kidney disease. Mitochondrial dysfunction has been considered a crucial contributor to maladaptive repair in acute kidney injury. Treatment with FG-4592, an inhibitor of hypoxia induc...

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Detalles Bibliográficos
Autores principales: Li, Xue, Jiang, Bo, Zou, Yu, Zhang, Jie, Fu, Yuan-Yuan, Zhai, Xiao-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915431/
https://www.ncbi.nlm.nih.gov/pubmed/35280255
http://dx.doi.org/10.3389/fphar.2021.788977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915431/
https://www.ncbi.nlm.nih.gov/pubmed/35280255
http://dx.doi.org/10.3389/fphar.2021.788977

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