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Roxadustat (FG-4592) Facilitates Recovery From Renal Damage by Ameliorating Mitochondrial Dysfunction Induced by Folic Acid
Incomplete recovery from acute kidney injury induced by folic acid is a major risk factor for progression to chronic kidney disease. Mitochondrial dysfunction has been considered a crucial contributor to maladaptive repair in acute kidney injury. Treatment with FG-4592, an inhibitor of hypoxia induc...
Autores principales: | Li, Xue, Jiang, Bo, Zou, Yu, Zhang, Jie, Fu, Yuan-Yuan, Zhai, Xiao-Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915431/ https://www.ncbi.nlm.nih.gov/pubmed/35280255 http://dx.doi.org/10.3389/fphar.2021.788977 |
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