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The cellular response to drug perturbation is limited: comparison of large-scale chemogenomic fitness signatures

BACKGROUND: Chemogenomic profiling is a powerful approach for understanding the genome-wide cellular response to small molecules. First developed in Saccharomyces cerevisiae, chemogenomic screens provide direct, unbiased identification of drug target candidates as well as genes required for drug res...

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Detalles Bibliográficos
Autores principales: Barazandeh, Marjan, Kriti, Divya, Nislow, Corey, Giaever, Guri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915488/
https://www.ncbi.nlm.nih.gov/pubmed/35277135
http://dx.doi.org/10.1186/s12864-022-08395-x