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The cellular response to drug perturbation is limited: comparison of large-scale chemogenomic fitness signatures
BACKGROUND: Chemogenomic profiling is a powerful approach for understanding the genome-wide cellular response to small molecules. First developed in Saccharomyces cerevisiae, chemogenomic screens provide direct, unbiased identification of drug target candidates as well as genes required for drug res...
Autores principales: | Barazandeh, Marjan, Kriti, Divya, Nislow, Corey, Giaever, Guri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915488/ https://www.ncbi.nlm.nih.gov/pubmed/35277135 http://dx.doi.org/10.1186/s12864-022-08395-x |
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