Distinct outcomes, ABL1 mutation profile, and transcriptome features between p190 and p210 transcripts in adult Philadelphia-positive acute lymphoblastic leukemia in the TKI era

BACKGROUND: The differential signaling and outcome of patients with p190 or p210 transcripts of BCR-ABL1 have been systematically investigated in chronic myeloid leukemia rather than in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+) ALL). METHODS: We analyzed the outcomes and A...

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Detalles Bibliográficos
Autores principales: Shi, Ting, Xie, Mixue, Chen, Li, Yuan, Wei, Wang, Yungui, Huang, Xin, Xie, Wanzhuo, Meng, Haitao, Lou, Yinjun, Yu, Wenjuan, Tong, Hongyan, Ye, Xiujin, Huang, Jinyan, Jin, Jie, Zhu, Honghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915539/
https://www.ncbi.nlm.nih.gov/pubmed/35277197
http://dx.doi.org/10.1186/s40164-022-00265-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915539/
https://www.ncbi.nlm.nih.gov/pubmed/35277197
http://dx.doi.org/10.1186/s40164-022-00265-2

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