Cargando…

Distinct outcomes, ABL1 mutation profile, and transcriptome features between p190 and p210 transcripts in adult Philadelphia-positive acute lymphoblastic leukemia in the TKI era

BACKGROUND: The differential signaling and outcome of patients with p190 or p210 transcripts of BCR-ABL1 have been systematically investigated in chronic myeloid leukemia rather than in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+) ALL). METHODS: We analyzed the outcomes and A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Ting, Xie, Mixue, Chen, Li, Yuan, Wei, Wang, Yungui, Huang, Xin, Xie, Wanzhuo, Meng, Haitao, Lou, Yinjun, Yu, Wenjuan, Tong, Hongyan, Ye, Xiujin, Huang, Jinyan, Jin, Jie, Zhu, Honghu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915539/ https://www.ncbi.nlm.nih.gov/pubmed/35277197 http://dx.doi.org/10.1186/s40164-022-00265-2

Ejemplares similares

Frequency of p190 and p210 BCR-ABL rearrangements and survival in Brazilian adult patients with acute lymphoblastic leukemia
por: de França Azevedo, Ilana, et al.
Publicado: (2014)

Chronic Myelogenous Leukemia with Double Philadelphia Chromosome and Coexpression of p210 and p190 Fusion Transcripts
por: da Cruz, Samara Silveira, et al.
Publicado: (2022)

Jak2/STAT6/c-Myc pathway is vital to the pathogenicity of Philadelphia-positive acute lymphoblastic leukemia caused by P190(BCR-ABL)
por: Qin, Run, et al.
Publicado: (2023)

Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia
por: Kaur, Pavinder, et al.
Publicado: (2007)

Coexistence of P190 and P210 BCR/ABL transcripts in chronic myeloid leukemia blast crisis resistant to imatinib
por: Junmei, Zhao, et al.
Publicado: (2015)

Differential signaling networks of Bcr–Abl p210 and p190 kinases in leukemia cells defined by functional proteomics
por: Reckel, S, et al.
Publicado: (2017)

Adult acute megakaryoblastic leukemia: rare association with cytopenias of undetermined significance and p210 and p190 BCR–ABL transcripts
por: Dima, Delia, et al.
Publicado: (2017)

P190(BCR-ABL1) in a Patient with Philadelphia Chromosome Positive T-Cell Acute Lymphoblastic Leukemia: A Rare Case Report and Review of Literature
por: Kohla, Samah, et al.
Publicado: (2021)

Prognostic significance of a normal karyotype in adult patients with BCR-ABL1-positive acute lymphoblastic leukemia in the tyrosine kinase inhibitor era
por: Shi, Ting, et al.
Publicado: (2020)

The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins
por: You, Liangshun, et al.
Publicado: (2016)

T‐cell blast crisis of chronic myelogenous leukemia presented with coexisting p210 and p190 BCR‐ABL transcripts and t(10;11)(q11;p15)
por: Xia, Ting, et al.
Publicado: (2020)

KLF5 controls glutathione metabolism to suppress p190-BCR-ABL+ B-cell lymphoblastic leukemia
por: Zhang, Cuiping, et al.
Publicado: (2018)

Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth
Publicado: (1994)

The P190, P210, and P230 Forms of the BCR/ABL Oncogene Induce a Similar Chronic Myeloid Leukemia–like Syndrome in Mice but Have Different Lymphoid Leukemogenic Activity
por: Li, Shaoguang, et al.
Publicado: (1999)

Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression
por: Tala, Ilona, et al.
Publicado: (2012)

p210(BCR‐ABL1)‐ Chronic myeloid leukemia presents with monocytosis
por: Wang, Xiaofei, et al.
Publicado: (2020)

Emergence of BCR-ABL1 (p190) in Acute Myeloid Leukemia Post-Gilteritinib Therapy
por: Kim, Heejeong, et al.
Publicado: (2023)

Standardization of BCR-ABL1 p210 Monitoring: From Nested to Digital PCR
por: Jovanovski, Aleksandar, et al.
Publicado: (2020)

Hypertriglyceridemia in Newly Diagnosed Acute Promyelocytic Leukemia
por: Sun, Jianai, et al.
Publicado: (2020)

Profiling of microRNAs in AML cells following overexpression or silencing of the VEGF gene
por: Li, Li, et al.
Publicado: (2017)

RUNX1 transactivates BCR‐ABL1 expression in Philadelphia chromosome positive acute lymphoblastic leukemia
por: Masuda, Tatsuya, et al.
Publicado: (2021)

Fatal hemorrhagic pneumonia in patients with hematologic diseases and Stenotrophomonas maltophilia bacteremia: a retrospective study
por: Zhu, Lixia, et al.
Publicado: (2021)

The targetable role of herpes virus-associated ubiquitin-specific protease (HAUSP) in p190 BCR-ABL leukemia
por: Carrà, Giovanna, et al.
Publicado: (2016)

Chronic Myeloid Leukemia With P190 BCR-ABL Translocation and Persistent Moderate Monocytosis: A Case Report
por: Gatti, Arianna, et al.
Publicado: (2018)

Characterization of p190-Bcr-Abl chronic myeloid leukemia reveals specific signaling pathways and therapeutic targets
por: Adnan-Awad, Shady, et al.
Publicado: (2020)

Clinical and histological features of primary testicular diffuse large B-cell lymphoma: a single center experience in China
por: Zhou, De, et al.
Publicado: (2017)

c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
por: Waldron, Todd, et al.
Publicado: (2011)

The e1a3 BCR-ABL1 Fusion Transcript in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
por: Langabeer, Stephen E.
Publicado: (2015)

Variant BCR-ABL1 fusion genes in adult Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia
por: Langabeer, Stephen E.
Publicado: (2017)

High-risk Combinations of Additional Chromosomal Abnormalities in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia: JALSG Ph+ALL TKI-SCT Study
por: Nishiwaki, Satoshi, et al.
Publicado: (2023)

P370: EFFICACY AND SAFETY OF THE THIRD-GENERATION TKI OLVEREMBATINIB IN ADULTS PH/BCR-ABL1-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA WITH T315I MUTATION AND RELAPSED/REFRACTORY DISEASE
por: Liu, Weiyang, et al.
Publicado: (2023)

HAG (Homoharringtonine, Cytarabine, G-CSF) Regimen for the Treatment of Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Meta-Analysis with 2,314 Participants
por: Xie, Mixue, et al.
Publicado: (2016)

Expression of chronic myeloid leukemia oncogenes BCR-ABL (P210) and BCR-ABL (T315I) affect cellular and humoral innate immunity in Drosophila melanogaster
por: Abubaker, Dana, et al.
Publicado: (2022)

A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia
por: Vinhas, Raquel, et al.
Publicado: (2018)

P210(T315I-BCR/ABL)转基因小鼠模型的建立与鉴定
Publicado: (2015)

Optimal Molecular Methods in Detecting p190(BCR-ABL) Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature
por: Sonu, Rebecca J., et al.
Publicado: (2015)

P190(BCR-ABL) Chronic Myeloid Leukemia Following a Course of S-1 Plus Oxaliplatin Therapy for Advanced Gastric Adenocarcinoma
por: Wang, Hua, et al.
Publicado: (2017)

A Rare Case of p190 BCR-ABL Chronic Myeloid Leukemia With a Very Good Response to Tyrosine Kinase Inhibitors
por: Gandhe, Nalinikumari, et al.
Publicado: (2021)

A case of e1a2 (minor, P190) BCR-ABL1-positive chronic myeloid leukemia in Korea
por: Choi, Yu Jeong, et al.
Publicado: (2021)

A Rare Case of p190 BCR-ABL B-cell Acute Lymphocytic Leukemia With Excellent Response to Hyper-CVAD and Ponatinib
por: DeRon, Nathan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2am8rvtcpqnrdi9ikqpljntsn8