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Inhibition of Nociception in a Preclinical Episodic Migraine Model by Dietary Supplementation of Grape Seed Extract Involves Activation of Endocannabinoid Receptors

Migraine is associated with peripheral and central sensitization of the trigeminal system and dysfunction of descending pain modulation pathways. Recently, dietary inclusion of grape seed extract (GSE) was shown to inhibit mechanical nociception in a preclinical model of chronic temporomandibular jo...

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Detalles Bibliográficos
Autores principales: Woodman, Sara E., Antonopoulos, Sophia R., Durham, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915558/
https://www.ncbi.nlm.nih.gov/pubmed/35295808
http://dx.doi.org/10.3389/fpain.2022.809352