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GPR171 Agonist Reduces Chronic Neuropathic and Inflammatory Pain in Male, But Not Female Mice

Chronic pain is a growing public health crisis that requires exigent and efficacious therapeutics. GPR171 is a promising therapeutic target that is widely expressed through the brain, including within the descending pain modulatory regions. Here, we explore the therapeutic potential of the GPR171 ag...

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Detalles Bibliográficos
Autores principales: Ram, Akila, Edwards, Taylor, McCarty, Ashley, Afrose, Leela, McDermott, Max V., Bobeck, Erin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915562/
https://www.ncbi.nlm.nih.gov/pubmed/35295419
http://dx.doi.org/10.3389/fpain.2021.695396