In vivo and in vitro Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development

Mu opioid receptor (MOPr) agonists are well-known and frequently used clinical analgesics but are also rewarding due to their highly addictive and often abusive properties. This may lead to opioid use disorder (OUD) a disorder that effects millions of people worldwide. Therefore, novel compounds are...

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Detalles Bibliográficos
Autores principales: Lee, Alex S., Tiwari, Suchi, Bishop, Isabel, Matossian, Vartan, Romaneschi, Nicole, Miyazaki, Takahiro, VanderVeen, Laurie, Zalevsky, Jonathan, DeFea, Kathryn, Cahill, Catherine M., Walwyn, Wendy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pain Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915576/
https://www.ncbi.nlm.nih.gov/pubmed/35295409
http://dx.doi.org/10.3389/fpain.2021.695962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915576/
https://www.ncbi.nlm.nih.gov/pubmed/35295409
http://dx.doi.org/10.3389/fpain.2021.695962

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