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Molecular docking investigation of the amantadine binding to the enzymes upregulated or downregulated in Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurodegenerative disease. Levodopa in combination with amantadine has a demonstrated efficacy in motility impairment. An extensive investigation of some enzymes described to be upregulated or downregulated in PD was made – adenylate kinase (AK), adenine pho...

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Detalles Bibliográficos
Autor principal: Ionescu, Mihaela Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915579/
https://www.ncbi.nlm.nih.gov/pubmed/35300368
http://dx.doi.org/10.5599/admet.854