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Validated DBS method for filgotinib quantitation in rat dried blood spots and its application to a pharmacokinetic study in rats

Filgotinib is a selective JAK1 (Janus kinase) inhibitor, showed efficacy in patients suffering from moderate-to-severe rheumatoid arthritis. In this paper, we present the data on the development and validation of a sensitive, selective and high-throughput LC-MS/MS (liquid chromatography with tandem...

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Detalles Bibliográficos
Autores principales: Dixit, Abhishek, Kiran, Vinay, Gabani, Bhavesh Babulal, Mullangi, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915582/
https://www.ncbi.nlm.nih.gov/pubmed/35300367
http://dx.doi.org/10.5599/admet.796