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Validated DBS method for filgotinib quantitation in rat dried blood spots and its application to a pharmacokinetic study in rats
Filgotinib is a selective JAK1 (Janus kinase) inhibitor, showed efficacy in patients suffering from moderate-to-severe rheumatoid arthritis. In this paper, we present the data on the development and validation of a sensitive, selective and high-throughput LC-MS/MS (liquid chromatography with tandem...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Association of Physical Chemists
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915582/ https://www.ncbi.nlm.nih.gov/pubmed/35300367 http://dx.doi.org/10.5599/admet.796 |