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Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models

An established pharmaceutical strategy to increase oral drug absorption of low solubility–high permeability drugs is to create nanoparticles of them. Reducing the size of the solid-state particles increases their dissolution and transport rate across the mucus barrier and the aqueous boundary layer....

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Detalles Bibliográficos
Autores principales: Dahlgren, David, Sjögren, Erik, Lennernäs, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915587/
https://www.ncbi.nlm.nih.gov/pubmed/35300192
http://dx.doi.org/10.5599/admet.881