The effect of drug ionization on lipid-based formulations for the oral delivery of anti-psychotics

Lipid-based formulations (LBFs) are well-known to improve the oral bioavailability of poorly water-soluble drugs (PWSDs) by presenting the drug to the gastrointestinal environment in a molecularly dispersed state, thus avoiding the rate-limiting dissolution step. Risperidone and lurasidone are antip...

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Detalles Bibliográficos
Autores principales: Meola, Tahlia R, Paxton, Kara, Joyce, Paul, Schultz, Hayley B, Prestidge, Clive A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2020
Materias:
Original Scientific Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915591/
https://www.ncbi.nlm.nih.gov/pubmed/35300191
http://dx.doi.org/10.5599/admet.830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915591/
https://www.ncbi.nlm.nih.gov/pubmed/35300191
http://dx.doi.org/10.5599/admet.830

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