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The effect of drug ionization on lipid-based formulations for the oral delivery of anti-psychotics
Lipid-based formulations (LBFs) are well-known to improve the oral bioavailability of poorly water-soluble drugs (PWSDs) by presenting the drug to the gastrointestinal environment in a molecularly dispersed state, thus avoiding the rate-limiting dissolution step. Risperidone and lurasidone are antip...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Association of Physical Chemists
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915591/ https://www.ncbi.nlm.nih.gov/pubmed/35300191 http://dx.doi.org/10.5599/admet.830 |