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Image-based dissolution analysis for tracking the surface stability of amorphous powders

Poor solubility of crystalline drugs can be overcome by amorphization – the production of high-energy disordered solid with improved solubility. However, the improved solubility comes at a cost of reduced stability; amorphous drugs are prone to recrystallization. Because of recrystallization, the in...

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Detalles Bibliográficos
Autores principales: Štukelj, Jernej, Agopov, Mikael, Yliruusi, Jouko, Strachan, Clare J., Svanbäck, Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915593/
https://www.ncbi.nlm.nih.gov/pubmed/35300194
http://dx.doi.org/10.5599/admet.839