Revisiting the application of Immobilized Artificial Membrane (IAM) chromatography to estimate in vivo distribution properties of drug discovery compounds based on the model of marketed drugs

Immobilized Artificial Membrane (IAM) chromatography columns have been used to model the in vivo distribution of drug discovery compounds. Regis Technologies Inc., the manufacturer, had to replace the silica support and consequently introduced a new IAM.PC.DD2 column that shows slightly different se...

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Detalles Bibliográficos
Autores principales: Valko, Klara, Rava, Silvia, Bunally, Shenaz, Anderson, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2020
Materias:
Original Scientific Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915595/
https://www.ncbi.nlm.nih.gov/pubmed/35299777
http://dx.doi.org/10.5599/admet.757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915595/
https://www.ncbi.nlm.nih.gov/pubmed/35299777
http://dx.doi.org/10.5599/admet.757

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