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Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome

Background and Aims: Irritable bowel syndrome (IBS), a functional pain disorder of gut-brain interactions, is characterized by a high placebo response in randomized clinical trials (RCTs). Catechol-O-methyltransferase (COMT) rs4680, which encodes high-activity (val) or low-activity (met) enzyme vari...

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Detalles Bibliográficos
Autores principales: Wang, Rui-Sheng, Lembo, Anthony J., Kaptchuk, Ted J., Cheng, Vivian, Nee, Judy, Iturrino, Johanna, Rao, Meenakshi, Loscalzo, Joseph, Silvester, Jocelyn A., Hall, Kathryn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915627/
https://www.ncbi.nlm.nih.gov/pubmed/35295415
http://dx.doi.org/10.3389/fpain.2021.775386