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Comparison of in vitro and in vivo Toxicity of Bupivacaine in Musculoskeletal Applications

The recent societal debate on opioid use in treating postoperative pain has sparked the development of long-acting, opioid-free analgesic alternatives, often using the amino-amide local anesthetic bupivacaine as active pharmaceutical ingredient. A potential application is musculoskeletal surgeries,...

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Detalles Bibliográficos
Autores principales: Steverink, Jasper G., Piluso, Susanna, Malda, Jos, Verlaan, Jorrit-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915669/
https://www.ncbi.nlm.nih.gov/pubmed/35295435
http://dx.doi.org/10.3389/fpain.2021.723883