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Profiling renal sodium transporters in mice with nephron Ift88 disruption: Association with sex, cysts, and blood pressure

Loss of nephron primary cilia due to disruption of the Ift88 gene results in sex‐ and age‐specific phenotypes involving renal cystogenesis, blood pressure (BP) and urinary Na(+) excretion. Previous studies demonstrated that male mice undergoing induction of nephron‐specific Ift88 gene disruption at...

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Detalles Bibliográficos
Autores principales: Hu, Chunyan, Lakshmipathi, Jayalakshmi, Stuart, Deborah, Kohan, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915723/
https://www.ncbi.nlm.nih.gov/pubmed/35274831
http://dx.doi.org/10.14814/phy2.15206