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Possible role of pannexin 1 channels and purinergic receptors in the pathogenesis and mechanism of action of SARS-CoV-2 and therapeutic potential of targeting them in COVID-19

Identifying signaling pathways and molecules involved in SARS-CoV-2 pathogenesis is pivotal for developing new effective therapeutic or preventive strategies for COVID-19. Pannexins (PANX) are ATP-release channels in the plasma membrane essential in many physiological and immune responses. Activatio...

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Detalles Bibliográficos
Autores principales: Nadeali, Zakiye, Mohammad-Rezaei, Fatemeh, Aria, Hamid, Nikpour, Parvaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915746/
https://www.ncbi.nlm.nih.gov/pubmed/35288174
http://dx.doi.org/10.1016/j.lfs.2022.120482