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Monoaminergic and Opioidergic Modulation of Brainstem Circuits: New Insights Into the Clinical Challenges of Pain Treatment?

The treatment of neuropathic pain remains a clinical challenge. Analgesic drugs and antidepressants are frequently ineffective, and opioids may induce side effects, including hyperalgesia. Recent results on brainstem pain modulatory circuits may explain those clinical challenges. The dual action of...

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Detalles Bibliográficos
Autores principales: Tavares, Isaura, Costa-Pereira, José Tiago, Martins, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915776/
https://www.ncbi.nlm.nih.gov/pubmed/35295506
http://dx.doi.org/10.3389/fpain.2021.696515