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Developmentally distinct CD4(+) T(reg) lineages shape the CD8(+) T cell response to acute Listeria infection

CD4(+) regulatory T cells (T(reg)(s)) must prevent immunopathology by cytotoxic CD8(+) T lymphocytes (CTLs) responding to acute infection and restore immune homeostasis following pathogen clearance, yet little is known about the specific populations or mechanisms governing these discrete events. We...

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Detalles Bibliográficos
Autores principales: Dolina, Joseph S., Lee, Joey, Moore, Eugene L., Hope, Jennifer L., Gracias, Donald T., Matsutani, Takaji, Chawla, Ashu, Greenbaum, Jason A., Linden, Joel, Schoenberger, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915796/
https://www.ncbi.nlm.nih.gov/pubmed/35239442
http://dx.doi.org/10.1073/pnas.2113329119