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Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation

There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current in vivo guideline studies. Under the umbrella of the Organisation for Economic Co-operation and Developm...

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Detalles Bibliográficos
Autores principales: Koch, Katharina, Bartmann, Kristina, Hartmann, Julia, Kapr, Julia, Klose, Jördis, Kuchovská, Eliška, Pahl, Melanie, Schlüppmann, Kevin, Zühr, Etta, Fritsche, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915868/
https://www.ncbi.nlm.nih.gov/pubmed/35295221
http://dx.doi.org/10.3389/ftox.2022.816370