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On the Use and Interpretation of Areola/Nipple Retention as a Biomarker for Anti-androgenic Effects in Rat Toxicity Studies

Areola/nipple retention (NR) is an established biomarker for an anti-androgenic mode of action in rat toxicity studies. It is a mandatory measurement under several OECD test guidelines and is typically assessed in combination with anogenital distance (AGD). Both NR and AGD are considered retrospecti...

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Detalles Bibliográficos
Autores principales: Schwartz, Camilla Lindgren, Christiansen, Sofie, Hass, Ulla, Ramhøj, Louise, Axelstad, Marta, Löbl, Nathalie Michelle, Svingen, Terje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915873/
https://www.ncbi.nlm.nih.gov/pubmed/35295101
http://dx.doi.org/10.3389/ftox.2021.730752