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DMSO Concentrations up to 1% are Safe to be Used in the Zebrafish Embryo Developmental Toxicity Assay

Dimethyl sulfoxide (DMSO) is a popular solvent for developmental toxicity testing of chemicals and pharmaceuticals in zebrafish embryos. In general, it is recommended to keep the final DMSO concentration as low as possible for zebrafish embryos, preferably not exceeding 100 μL/L (0.01%). However, hi...

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Detalles Bibliográficos
Autores principales: Hoyberghs, Jente, Bars, Chloé, Ayuso, Miriam, Van Ginneken, Chris, Foubert, Kenn, Van Cruchten, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915880/
https://www.ncbi.nlm.nih.gov/pubmed/35295145
http://dx.doi.org/10.3389/ftox.2021.804033