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O-GlcNAcylation regulates epidermal growth factor receptor intracellular trafficking and signaling

Ligand-stimulated epidermal growth factor receptor (EGFR) signaling plays fundamental roles in normal cell physiology, such as cell growth, cell proliferation, and cell survival. Deregulation of EGFR signaling contributes to the development and progression of diseases including cancer. Despite its e...

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Detalles Bibliográficos
Autores principales: Wu, Liming, Cheng, Yaxian, Geng, Didi, Fan, Zhiya, Lin, Bingyi, Zhu, Qiang, Li, Jingchao, Qin, Weijie, Yi, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915906/
https://www.ncbi.nlm.nih.gov/pubmed/35239437
http://dx.doi.org/10.1073/pnas.2107453119