Mapping Mechanistic Pathways of Acute Oral Systemic Toxicity Using Chemical Structure and Bioactivity Measurements

Regulatory agencies around the world have committed to reducing or eliminating animal testing for establishing chemical safety. Adverse outcome pathways can facilitate replacement by providing a mechanistic framework for identifying the appropriate non-animal methods and connecting them to apical ad...

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Detalles Bibliográficos
Autores principales: Edwards, Stephen W., Nelms, Mark, Hench, Virginia K., Ponder, Jessica, Sullivan, Kristie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915918/
https://www.ncbi.nlm.nih.gov/pubmed/35295211
http://dx.doi.org/10.3389/ftox.2022.824094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915918/
https://www.ncbi.nlm.nih.gov/pubmed/35295211
http://dx.doi.org/10.3389/ftox.2022.824094

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