Exercise-Generated β-Aminoisobutyric Acid (BAIBA) Reduces Cardiomyocyte Metabolic Stress and Apoptosis Caused by Mitochondrial Dysfunction Through the miR-208b/AMPK Pathway

OBJECTIVE: To explore the cardioprotective effects of exercise-derived β-aminoisobutyric (BAIBA) on cardiomyocyte apoptosis and energy metabolism in a rat model of heart failure (HF). METHODS: In male Sprague-Dawley rats (8-week-old), myocardial infarction (MI) was used to induce HF by ligating the...

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Detalles Bibliográficos
Autores principales: Yu, Yanan, Chen, Wewei, Yu, Ming, Liu, Jinsha, Sun, Huan, Yang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915946/
https://www.ncbi.nlm.nih.gov/pubmed/35282369
http://dx.doi.org/10.3389/fcvm.2022.803510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915946/
https://www.ncbi.nlm.nih.gov/pubmed/35282369
http://dx.doi.org/10.3389/fcvm.2022.803510

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