Cargando…
Strain and rupture of HIV-1 capsids during uncoating
Viral replication in HIV-1 relies on a fullerene-shaped capsid to transport genetic material deep into the nucleus of an infected cell. Capsid stability is linked to the presence of cofactors, including inositol hexakisphosphates (IP(6)) that bind to pores found in the capsid. Using extensive all-at...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915963/ https://www.ncbi.nlm.nih.gov/pubmed/35238630 http://dx.doi.org/10.1073/pnas.2117781119 |