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An Fgf–Shh positive feedback loop drives growth in developing unpaired fins
The origin and diversification of appendage types is a central question in vertebrate evolution. Understanding the genetic mechanisms that underlie fin and limb development can reveal relationships between different appendages. Here we demonstrate, using chemical genetics, a mutually agonistic inter...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916008/ https://www.ncbi.nlm.nih.gov/pubmed/35238632 http://dx.doi.org/10.1073/pnas.2120150119 |