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An Fgf–Shh positive feedback loop drives growth in developing unpaired fins

The origin and diversification of appendage types is a central question in vertebrate evolution. Understanding the genetic mechanisms that underlie fin and limb development can reveal relationships between different appendages. Here we demonstrate, using chemical genetics, a mutually agonistic inter...

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Detalles Bibliográficos
Autores principales: Hawkins, M. Brent, Jandzik, David, Tulenko, Frank J., Cass, Amanda N., Nakamura, Tetsuya, Shubin, Neil H., Davis, Marcus C., Stock, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916008/
https://www.ncbi.nlm.nih.gov/pubmed/35238632
http://dx.doi.org/10.1073/pnas.2120150119